Studies on the Analgesic Potential of leaf Extracts of Allium humile on Swiss albino mice

2015 European Researcher Cilt 2014/14, Sayı 83

İngilizce öz

Allium humile is a medicinal plant found at the Alpine Himalayas of Uttarakhand at
altitute of 2500-3000 meters height of sea level. In India, Allium humile, is used by local people as
a spice and in ethano-medicine. In the present study, Allium humile leaves were explored for their
analgesic potential on experimental model and compared to standard drugs. Allium humile at the
doses of 100 mg/kg and aspirin 25 mg/kg exhibited significant (p>0.05) inhibition of the control
writhes at the rate of 64.25%, 44.54%, 44.54% and 59.89% respectively when compared to that of
control. Thus, methanolic extract of the plant can be fully explored for its analgesic potential which
has not been reported so far. The plant extract showed a relative low toxicity hence justifies the
folkloric use of plant by the local people in Western Himalayan region for curing inflammation and
painful conditions.

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